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HKU Unveils Innovative Portable AI Optical Sensing Device for Rapid, Non-Invasive Cancer Risk Detection

Cancer remains a critical health challenge globally. In 2023, the Hong Kong Cancer Registry recorded close to 38,000 new cancer cases and nearly 15,000 cancer-related deaths. Faced with the continuously rising number of cases, society's demand for detection solutions that can be used for early screening and long-term monitoring is also increasing accordingly. Currently researchers are developing a range of innovative detection approaches, aiming to complement current techniques and enable a more comprehensive framework for cancer detection, better supporting public health monitoring needs.    Professor Chi-Ming CHE, Zhou Guangzhao Professor in Natural Sciences and Chair Professor of Chemistry, Department of Chemistry, Faculty of Science, The University of Hong Kong (HKU), and the Laboratory for Synthetic Chemistry and Chemical Biology Limited (LSCCB), and Dr Wei Liu, Department of Chemistry, Faculty of Science, HKU, and LSCCB, have developed an innovative portable AI-enabled optical sensing device that enables rapid, non-invasive cancer risk detection using just a saliva sample. This innovative technology integrates advanced chemical sensing with artificial intelligence and was awarded a Gold Medal with Congratulations of the Jury at the 51st International Exhibition of Inventions of Geneva (2026), recognising its scientific excellence and strong potential for practical application.    This innovative technology was awarded a Gold Medal with Congratulations of the Jury at the 51st International Exhibition of Inventions of Geneva (2026)  Non-Invasive, Fast and Accessible Detection   This newly developed device represents a major advancement in cancer detection by offering a non-invasive, fast and user-friendly alternative to traditional methods. Designed for portability and ease of use, the device allows individuals to conduct tests independently through a mobile application, without the need for specialised medical personnel or large-scale equipment. The detection process is completed in under 10 minutes.  The schematic diagram showing the detection process of this innovative technology.  Professor Che said, “Using saliva instead of tissue samples enables us to minimise discomfort while reducing the risks associated with invasive procedures. This makes it a promising early-stage auxiliary detection tool for hospital examinations. Its convenience makes it particularly suitable for high-risk individuals, including those with a family history of cancer and patients requiring regular follow-up after treatment.  Innovative Luminescent Technology Meets Artificial Intelligence  At the core of this innovation is a novel class of luminescent metal complexes invented by Professor Che, which selectively bind to DNA damage sites – key indicators associated with cancer development. When bound to damaged DNA, especially mismatched DNA, the complexes exhibit a dramatic change in photo-luminescence compared to normal DNA, enabling detection using a highly sensitive device. The optical signal is captured by a miniature spectrometer, engineered by Dr Wei Liu, and then translated into actionable insights through AI-powered analysis. The integration of advanced chemical sensing with artificial intelligence creates a powerful platform that bridges molecular diagnostics and digital health technologies.  The innovative technologies: (a) The luminescent metal complexes that selectively bind to mismatched DNA, developed by Prof. Che; (b) The portable spectral device that captures the luminescent signal, developed by Dr. Liu. From Laboratory Breakthrough to Clinical Impact Professor Che emphasised, “This device is not intended to replace clinical diagnoses, but rather to serve as a complementary tool for rapid detection and continuous monitoring.” Preliminary studies involving patients with breast cancer and nasopharyngeal carcinoma have demonstrated strong capability in distinguishing between healthy and affected individuals. The research team is currently collaborating with clinical oncologists across multiple hospitals to conduct larger-scale validation studies covering a broader spectrum of cancer types. This initiative reflects HKU and LSCCB’s commitment to translating cutting-edge scientific research into practical solutions that address pressing healthcare challenges and deliver meaningful societal impact. 

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HKU Nobel Laureate Professor Ferenc Krausz Elected as International Member of U.S. National Academy of Sciences

Professor Ferenc KRAUSZ, Chair Professor of Laser Physics in the Department of Physics, Faculty of Science at The University of Hong Kong (HKU), has been elected as an International Member of the National Academy of Sciences, USA (NAS), in recognition of his outstanding contributions to ultrafast laser science and attosecond physics. Professor Xiang ZHANG, President and Vice-Chancellor of HKU extended his congratulations, remarking, “Professor Krausz’s work has fundamentally redefined the boundaries of what we can measure, allowing us to witness the swiftest processes in the physical world. His election is a profound recognition of a scientist who looks where others once thought it was impossible to see. At HKU, we strive to be a home for the pursuit of fundamental truths, with a view to inspiring the next generation of scholars to push beyond the established limits of human knowledge.” The NAS recently announced the election of 120 members and 25 international members in recognition of their distinguished and continuing achievements in original research. Reflecting on the honour, Professor Krausz said: “I am deeply grateful for this recognition from the National Academy of Sciences. It reflects many years of collaborative work, and I look forward to continuing to advance attosecond science and its applications.” Professor Krausz, who was awarded the Nobel Prize in Physics in 2023, is widely recognised for pioneering attosecond metrology, enabling the observation of electron dynamics on their natural timescales. His work has opened new frontiers in physics, chemistry, and materials science, with far-reaching implications for both fundamental research and technological innovation. About Professor Ferenc Krausz A Hungarian-born Austrian physicist and a pioneer of attosecond science, Professor Krausz earned his doctorate in laser physics with distinction from the Vienna University of Technology in 1991 and completed his habilitation in 1993. He continued his academic career at the Vienna University of Technology, where he joined as an assistant professor in 1996 and was promoted to full professor in 1999. Since 2004, he has been holding leadership roles as Director of the Max Planck Institute of Quantum Optics and as Chair of Experimental Physics - Laser Physics at Ludwig Maximilian University in Munich. He founded the Centre for Advanced Laser Applications in Munich in 2015 and the Center for Molecular Fingerprinting (CMF) in 2019. With CMF (cmf.hu), he took the lead in establishing a new type of large-scale prospective longitudinal cohort study, “h4h.hu”, aimed at laying the foundations for personalised preventive healthcare. To this end, he recently initiated a global alliance, “Protecting.Health”, bringing together CMF, LMU and HKU.   His accolades include the Nobel Prize in Physics (2023), awarded for his experiments with attosecond pulses of light, which he shared with Pierre Agostini and Anne L’Huillier. He is also a recipient of the BBVA Foundation Frontiers of Knowledge Award (2023), the Wolf Prize in Physics (2022), and the King Faisal International Prize for Science (2013). His work has contributed to advances in precision measurement and a deeper understanding of fundamental processes in matter.

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HKU Research Team to Develop “Short-Wavelength Infrared Spectrometer” for China’s Tianwen-3 Mission Advancing the Search for Signs of Life on Mars

A research team from the Department of Earth and Planetary Sciences will participate in China’s planetary exploration mission, Tianwen-3. According to the selection results recently released by the China National Space Administration, the “Short-Wavelength Infrared Spectrometer”, led and developed by HKU, has been officially selected as a payload for deployment on the service module of the Tianwen3 mission. The instrument will play a critical role in forecasting dust storms during landing manoeuvres, searching for biosignatures, detecting hydrous minerals, and surveying Martian resources.  In addition, the orbiter will carry three collaborative payloads, including the COSPAR-led Martian PEX spectrometer, on which the HKU Laboratory for Space Research participates alongside Shenzhen University. Tianwen-3 mission is China’s first Mars Sample Return mission. Scheduled for launch in 2028, with sample return planned for 2031, the mission aims to address fundamental scientific questions, including the uniqueness of life on Earth and the universality of biochemical mechanisms in the universe. Professor Xiang ZHANG, President and Vice-Chancellor of HKU, commented, “HKU is honoured to participate in the Tianwen-3 planetary exploration mission. The selection of our research project as a mission payload reflects the University’s deep-seated expertise in planetary science and deep-space exploration, while marking a significant contribution to the nation’s strategic advancement as a leading space power. We remain committed to deepening our frontier research to further expand the boundaries of human knowledge.” The project is led by Professor Yiliang LI of the Department of Earth and Planetary Sciences at HKU, with major collaborating institutions including Zhejiang University and the Chinese Academy of Sciences’ Changchun Institute of Optics, Fine Mechanics, and Physics. The instrument will be used for key investigations, including forecasting dust storms during the landing maneuver, searching for biosignatures, detecting hydrous minerals, and surveying resources on Mars. The orbital spectrometer will undertake three primary tasks: 1. To monitor the potential emergence and development of dust storms, thereby guiding the safe landing of the lander at sites of highest scientific value. 2. To provide detailed, high-spatial-resolution mineralogical mapping of candidate landing sites from orbit, supporting final-stage landing site selection for the Tianwen-3 mission. 3. Following completion of the sample return phase, the instrument will remain in orbit for at least five years to conduct sustained observations of Mars’s low-latitude regions. Professor Li stated: “This mission marks a significant contribution from Hong Kong’s scientific community to the nation’s deep space exploration programme. Using hyperspectral imaging technology, we will directly search for biosignatures and hydrous minerals on Mars, which is fundamentally important for understanding the distribution of life in the universe.” Professor Li has served as a core member of both the Landing Site Selection Team and the Mission Science Team of the Tianwen-3 mission. The selection of this payload demonstrates HKU’s international competitiveness in Earth and planetary sciences while fostering interdisciplinary synergy across science and engineering in Hong Kong. Professor Li further noted that the project aligns with two concurrent developments: “First, the continued expansion of HKU’s research capabilities in Earth and planetary sciences, particularly in cosmochemistry and astrobiology focusing on solar system bodies such as asteroids, Mars and Jupiter; and second, the Hong Kong SAR Government’s strategic initiative to cultivate a local aerospace industry, by leveraging the region’s geographical advantages.” Professor Yiliang LI of HKU Earth and Planetary Sciences.

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The appearance of the device.

HKU Unveils Innovative Portable AI Optical Sensing Device for Rapid, Non-Invasive Cancer Risk Detection

Cancer remains a critical health challenge globally. In 2023, the Hong Kong Cancer Registry recorded close to 38,000 new cancer cases and nearly 15,000 cancer-related deaths. Faced with the continuously rising number of cases, society's demand for detection solutions that can be used for early screening and long-term monitoring is also increasing accordingly. Currently researchers are developing a range of innovative detection approaches, aiming to complement current techniques and enable a more comprehensive framework for cancer detection, better supporting public health monitoring needs.    Professor Chi-Ming CHE, Zhou Guangzhao Professor in Natural Sciences and Chair Professor of Chemistry, Department of Chemistry, Faculty of Science, The University of Hong Kong (HKU), and the Laboratory for Synthetic Chemistry and Chemical Biology Limited (LSCCB), and Dr Wei Liu, Department of Chemistry, Faculty of Science, HKU, and LSCCB, have developed an innovative portable AI-enabled optical sensing device that enables rapid, non-invasive cancer risk detection using just a saliva sample. This innovative technology integrates advanced chemical sensing with artificial intelligence and was awarded a Gold Medal with Congratulations of the Jury at the 51st International Exhibition of Inventions of Geneva (2026), recognising its scientific excellence and strong potential for practical application.    This innovative technology was awarded a Gold Medal with Congratulations of the Jury at the 51st International Exhibition of Inventions of Geneva (2026)  Non-Invasive, Fast and Accessible Detection   This newly developed device represents a major advancement in cancer detection by offering a non-invasive, fast and user-friendly alternative to traditional methods. Designed for portability and ease of use, the device allows individuals to conduct tests independently through a mobile application, without the need for specialised medical personnel or large-scale equipment. The detection process is completed in under 10 minutes.  The schematic diagram showing the detection process of this innovative technology.  Professor Che said, “Using saliva instead of tissue samples enables us to minimise discomfort while reducing the risks associated with invasive procedures. This makes it a promising early-stage auxiliary detection tool for hospital examinations. Its convenience makes it particularly suitable for high-risk individuals, including those with a family history of cancer and patients requiring regular follow-up after treatment.  Innovative Luminescent Technology Meets Artificial Intelligence  At the core of this innovation is a novel class of luminescent metal complexes invented by Professor Che, which selectively bind to DNA damage sites – key indicators associated with cancer development. When bound to damaged DNA, especially mismatched DNA, the complexes exhibit a dramatic change in photo-luminescence compared to normal DNA, enabling detection using a highly sensitive device. The optical signal is captured by a miniature spectrometer, engineered by Dr Wei Liu, and then translated into actionable insights through AI-powered analysis. The integration of advanced chemical sensing with artificial intelligence creates a powerful platform that bridges molecular diagnostics and digital health technologies.  The innovative technologies: (a) The luminescent metal complexes that selectively bind to mismatched DNA, developed by Prof. Che; (b) The portable spectral device that captures the luminescent signal, developed by Dr. Liu. From Laboratory Breakthrough to Clinical Impact Professor Che emphasised, “This device is not intended to replace clinical diagnoses, but rather to serve as a complementary tool for rapid detection and continuous monitoring.” Preliminary studies involving patients with breast cancer and nasopharyngeal carcinoma have demonstrated strong capability in distinguishing between healthy and affected individuals. The research team is currently collaborating with clinical oncologists across multiple hospitals to conduct larger-scale validation studies covering a broader spectrum of cancer types. This initiative reflects HKU and LSCCB’s commitment to translating cutting-edge scientific research into practical solutions that address pressing healthcare challenges and deliver meaningful societal impact. 

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HKU Nobel Laureate Professor Ferenc Krausz Elected as International Member of U.S. National Academy of Sciences

Professor Ferenc KRAUSZ, Chair Professor of Laser Physics in the Department of Physics, Faculty of Science at The University of Hong Kong (HKU), has been elected as an International Member of the National Academy of Sciences, USA (NAS), in recognition of his outstanding contributions to ultrafast laser science and attosecond physics. Professor Xiang ZHANG, President and Vice-Chancellor of HKU extended his congratulations, remarking, “Professor Krausz’s work has fundamentally redefined the boundaries of what we can measure, allowing us to witness the swiftest processes in the physical world. His election is a profound recognition of a scientist who looks where others once thought it was impossible to see. At HKU, we strive to be a home for the pursuit of fundamental truths, with a view to inspiring the next generation of scholars to push beyond the established limits of human knowledge.” The NAS recently announced the election of 120 members and 25 international members in recognition of their distinguished and continuing achievements in original research. Reflecting on the honour, Professor Krausz said: “I am deeply grateful for this recognition from the National Academy of Sciences. It reflects many years of collaborative work, and I look forward to continuing to advance attosecond science and its applications.” Professor Krausz, who was awarded the Nobel Prize in Physics in 2023, is widely recognised for pioneering attosecond metrology, enabling the observation of electron dynamics on their natural timescales. His work has opened new frontiers in physics, chemistry, and materials science, with far-reaching implications for both fundamental research and technological innovation. About Professor Ferenc Krausz A Hungarian-born Austrian physicist and a pioneer of attosecond science, Professor Krausz earned his doctorate in laser physics with distinction from the Vienna University of Technology in 1991 and completed his habilitation in 1993. He continued his academic career at the Vienna University of Technology, where he joined as an assistant professor in 1996 and was promoted to full professor in 1999. Since 2004, he has been holding leadership roles as Director of the Max Planck Institute of Quantum Optics and as Chair of Experimental Physics - Laser Physics at Ludwig Maximilian University in Munich. He founded the Centre for Advanced Laser Applications in Munich in 2015 and the Center for Molecular Fingerprinting (CMF) in 2019. With CMF (cmf.hu), he took the lead in establishing a new type of large-scale prospective longitudinal cohort study, “h4h.hu”, aimed at laying the foundations for personalised preventive healthcare. To this end, he recently initiated a global alliance, “Protecting.Health”, bringing together CMF, LMU and HKU.   His accolades include the Nobel Prize in Physics (2023), awarded for his experiments with attosecond pulses of light, which he shared with Pierre Agostini and Anne L’Huillier. He is also a recipient of the BBVA Foundation Frontiers of Knowledge Award (2023), the Wolf Prize in Physics (2022), and the King Faisal International Prize for Science (2013). His work has contributed to advances in precision measurement and a deeper understanding of fundamental processes in matter.

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Distinguished guests and leading scientists from the international astronomical community gathered at the APRIM 2026.

HKU LSR Organises APRIM 2026 to Advance Space Research and International Collaboration

Taking place from May 4–8, 2026, the Asia-Pacific Regional International Astronomical Union Meeting (APRIM) 2026 officially opened yesterday at the Hong Kong Convention and Exhibition Centre. Organised by the Laboratory for Space Research (LSR) at the HKU Faculty of Science, this prestigious triennial event is being hosted in Hong Kong for the first time. APRIM 2026 brings together nearly 600 leading scholars from more than 40 countries and regions, making it the largest astronomical conference ever held in Hong Kong.   With the theme “Science, Cooperation and Friendship – Working Together Across the Asia-Pacific Region within the IAU Framework,” APRIM 2026 features dedicated sessions that explore space sustainability and frontier topics such as lunar bases. The programme offers a comprehensive agenda, with discussions ranging from black holes and exoplanets to orbital debris and the expanding space economy.   At the opening ceremony, Kevin Choi Kit-ming, Permanent Secretary for Innovation, Technology and Industry, announced substantial government support for aerospace research, stating: “Hong Kong has already attracted 16 aerospace companies to the city, thanks to the nation’s 15th Five-Year Plan (2026-30), elevating the space economy as a strategic pillar,” he said. He also announced over HK$100 million in government funding for six flagship aerospace R&D projects, including a HKU-developed short-wavelength infrared spectrometer selected as a payload for China’s Tianwen 3 Mars mission, scheduled for 2028.   Professor Quentin Parker, Director of the LSR and one of the event’s organisers, highlighted Hong Kong’s unique advantages as an emerging global hub for space sustainability, citing strengths in common law, fintech, international connectivity, and intellectual property protection. “APRIM represents far more than an academic conference. We can become a global hub for space sustainability,” he said.   The event’s impact extends beyond the main sessions, with a parallel meeting on space sustainability, a public open day, and an outreach conference running concurrently. These initiatives underscore Hong Kong’s ambition to lead international discussions on satellite regulation and the long-term stewardship of the space environment.   As APRIM 2026 continues throughout the week, the LSR reaffirms its commitment to advancing frontier research, fostering global partnerships, and supporting Hong Kong’s role in the new space economy and international space research.   For more details about APRIM 2026: https://aprim2026.org    Professor Quentin Parker, Director of the Laboratory for Space Research (LSR).   A group photograph showcasing the attending scientists and delegates was captured during the opening ceremony of APRIM 2026.    A panel of distinguished astronomers and Shaw Prize laureates engaged in a stimulating discussion during APRIM 2026. Video  

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HKU Research Team to Develop “Short-Wavelength Infrared Spectrometer” for China’s Tianwen-3 Mission Advancing the Search for Signs of Life on Mars

A research team from the Department of Earth and Planetary Sciences will participate in China’s planetary exploration mission, Tianwen-3. According to the selection results recently released by the China National Space Administration, the “Short-Wavelength Infrared Spectrometer”, led and developed by HKU, has been officially selected as a payload for deployment on the service module of the Tianwen3 mission. The instrument will play a critical role in forecasting dust storms during landing manoeuvres, searching for biosignatures, detecting hydrous minerals, and surveying Martian resources.  In addition, the orbiter will carry three collaborative payloads, including the COSPAR-led Martian PEX spectrometer, on which the HKU Laboratory for Space Research participates alongside Shenzhen University. Tianwen-3 mission is China’s first Mars Sample Return mission. Scheduled for launch in 2028, with sample return planned for 2031, the mission aims to address fundamental scientific questions, including the uniqueness of life on Earth and the universality of biochemical mechanisms in the universe. Professor Xiang ZHANG, President and Vice-Chancellor of HKU, commented, “HKU is honoured to participate in the Tianwen-3 planetary exploration mission. The selection of our research project as a mission payload reflects the University’s deep-seated expertise in planetary science and deep-space exploration, while marking a significant contribution to the nation’s strategic advancement as a leading space power. We remain committed to deepening our frontier research to further expand the boundaries of human knowledge.” The project is led by Professor Yiliang LI of the Department of Earth and Planetary Sciences at HKU, with major collaborating institutions including Zhejiang University and the Chinese Academy of Sciences’ Changchun Institute of Optics, Fine Mechanics, and Physics. The instrument will be used for key investigations, including forecasting dust storms during the landing maneuver, searching for biosignatures, detecting hydrous minerals, and surveying resources on Mars. The orbital spectrometer will undertake three primary tasks: 1. To monitor the potential emergence and development of dust storms, thereby guiding the safe landing of the lander at sites of highest scientific value. 2. To provide detailed, high-spatial-resolution mineralogical mapping of candidate landing sites from orbit, supporting final-stage landing site selection for the Tianwen-3 mission. 3. Following completion of the sample return phase, the instrument will remain in orbit for at least five years to conduct sustained observations of Mars’s low-latitude regions. Professor Li stated: “This mission marks a significant contribution from Hong Kong’s scientific community to the nation’s deep space exploration programme. Using hyperspectral imaging technology, we will directly search for biosignatures and hydrous minerals on Mars, which is fundamentally important for understanding the distribution of life in the universe.” Professor Li has served as a core member of both the Landing Site Selection Team and the Mission Science Team of the Tianwen-3 mission. The selection of this payload demonstrates HKU’s international competitiveness in Earth and planetary sciences while fostering interdisciplinary synergy across science and engineering in Hong Kong. Professor Li further noted that the project aligns with two concurrent developments: “First, the continued expansion of HKU’s research capabilities in Earth and planetary sciences, particularly in cosmochemistry and astrobiology focusing on solar system bodies such as asteroids, Mars and Jupiter; and second, the Hong Kong SAR Government’s strategic initiative to cultivate a local aerospace industry, by leveraging the region’s geographical advantages.” Professor Yiliang LI of HKU Earth and Planetary Sciences.

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HKU Science Project on Peptide Drug Innovation Secures RAISe+ Funding

A research project led by Professor Xuechen LI from the Department of Chemistry has been selected for funding under the third round of the Research, Academic and Industry Sectors One-plus (RAISe+) Scheme by the Innovation and Technology Commission (ITC). The project, Peptide Drug Innovation and Discovery, focuses on advancing next-generation peptide therapeutics, a class of drugs that use short chains of amino acids to precisely target biological processes. With the global peptide drug market continuing to grow rapidly, the project aims to address key limitations of conventional peptide drugs, including their instability, poor permeability, and short half-lives. By tackling these challenges, the team aims to develop peptide drug candidates with improved efficacy and broader clinical potential, helping to develop more accessible therapies for patients worldwide. The project also positions Hong Kong to play a more active role in the rapidly expanding peptide therapeutics landscape. Professor Li is the Morningside Professor in Chemical Biology and Chair Professor of Medicinal Chemistry and Chemical Biology at HKU Chemistry. His research focuses on chemical biology, peptide science, and drug discovery. The RAISe+ scheme, supported by the ITC of the HKSAR Government, aims to foster cooperation between the research, academic, and industry sectors to accelerate the commercialisation of R&D outcomes. By bridging the gap between laboratories and industrial applications, these projects are poised to deliver substantial societal and economic benefits.   

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Exploring Italy’s Scientific and Cultural Heritage: A Journey from Trieste to Venice

Three PhD students, Min LONG, Menghan SONG, and Ting-Tung WANG, from the group of Professor Zi Yang MENG in the Department of Physics, embarked on a scientific journey at the Abdus Salam International Centre for Theoretical Physics (ICTP) in Trieste, Italy, last December. Below, they share their experiences of exchanging knowledge and exploring the rich history and culture of Trieste and Venice.   Trieste: A City of Borders and History Trieste is a port city that once served as the main sea gate of the Austro-Hungarian Empire. Today, the empire is gone, and the city is Italian, but its unique identity persists. The architecture reflects its imperial past, with grand, sombre buildings from the Habsburg era facing the waterfront. The piazzas are wide and open to the sea breeze, and historic cafés invite you to enjoy coffee amid a blend of influences – more reminiscent of Vienna than Rome. The light is Adriatic, but the soul is mixed, reflecting a city of borders and changed maps. Sculpture in Piazza Unità d'Italia In December 2025, we visited the Abdus Salam International Centre for Theoretical Physics (ICTP). The Centre is a cluster of functional buildings on the outskirts of Trieste. Founded by the late Nobel Laureate Abdus Salam and Italian physicist Paolo Budinich, it is a hub for scientists from all over the world, especially those from developing countries. It is a tranquil place with plain corridors and a slow pace. Here, we participated in a two-week Advanced School and Conference on Quantum Matter. The event intertwined pedagogical lectures from the school and conference-style talks on Quantum Spin Liquids.   At ICTP, we had enriching conversations with research scientists Marcello Dalmonte, Yin Ran, and Cenke Xu. Topics ranged from cutting-edge hybrid Monte Carlo simulations of fractional quantum Hall states—platforms for quantum computation—to the intricate techniques of entanglement microscopy that reveal the deep organising principles governing many-particle systems. A highlight was the exploration of the Chiral graviton—a phenomenon akin to ripples in the emergent internal geometry of the electronic universe—and its realisation in the fractional Chern insulator. These fruitful exchanges have already led to our recent preprint, Chiral Graviton Modes in Fermionic Fractional Chern Insulator, and we anticipate further collaborations, including a forthcoming visit to HKU by an Italian scholar.   Many distinguished Chinese physicists, such as Xi Dai and Lu Yu, have worked at ICTP. They did important work and helped facilitate knowledge exchange with their home institutions. ICTP has served as a bridge, facilitating knowledge exchange through sustained, dedicated work. In the cafeteria, a dozen languages mingle, unified by the language of physics. It is a truly inspiring place.   The Grand Canal     The ICTP campus   From Trieste to Venice: A Coastal Journey From Trieste, we took a two-hour train ride along the coast to Venice. Venice is unlike any other city. Stepping out of the station, you are greeted by the water of the Grand Canal. There are no cars, only boats. The city is built on millions of wooden pilings driven into the mud of the Venetian Lagoon. Once a powerful maritime republic, its wealth is evident in landmarks like the Doge’s Palace and the Basilica, with gold accents and ornate ceilings. Yet, the true essence of Venice lies in its small details. While in Venice, we took a boat out to Murano, the island famed for glassmaking. Watching a master shape molten glass into a delicate horse in just minutes revealed the skill and artistry behind this ancient craft. Back in the city, the streets are canals. The sidewalks are narrow. We crossed small bridges and passed shops displaying traditional Venetian Carnival masks—some simple white, others gilded with long beaks. These masks were once worn during festivals to conceal identity, allowing people to step outside their usual roles. Today, they are mostly made for tourists, but they still carry a sense of the city’s old mystery.   From left: Menghan Song, Ting-Tung Wang and Min Long As the light faded, the crowds departed on their boats, and the city quietened. We could hear the water lapping against the ancient stones. We found a small place to eat—simple fare of fish, pasta, and house wine. The next day, on the return train along the coast, we reflected on the two cities. Trieste, solid and serious on its land, is focused on fundamental questions about the universe. Venice, floating on its borrowed time, stands as a beautiful relic of the past. Both are real, and both tell a true story. That, in itself, is enough.

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