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Teaching Staff

Dr. TOY, Patrick Henry

Dr. TOY, Patrick Henry

Department of Chemistry, Faculty of Science, HKU

B.Sc. (Ohio State University ); Ph.D. (Wayne State University)

  • 2859 2167
  • 404 Chong Yuet Ming Chemistry Building, University of Hong Kong, Pok Fu Lam Road, Hong Kong

Research area:

  • Organocatalysis in Organic Synthesis
  • Natural Products Synthesis
  • Polymer-Supported Catalysts, Reagents and Ligands



  1. Yang, Y.-C.; Leung, D. Y. C.; Toy, P. H. Rasta Resin-TBD as a Reusable Catalyst for Transesterification Reactions. Synlett2013, 1870-1874.
  2. Lu, J.; Toy, P. H. Multifunctional Organic Polymeric Catalysts and Reagents. Pure Appl. Chem.2013, 85, 543-556.
  3. Wu, B.; Li, K.; Toy, P. H. Synthesis of Hydroxy-α-Sanshool. Synlett2012, 2564-2566.
  4. Diebold, C.; Lu, J.; Becht, J.-M.; Toy, P. H.; Le Drian, C. An Efficient and Reusable Palladium Catalyst Supported on a Rasta Resin for Suzuki-Miyaura Cross-Couplings. Eur. J. Org. Chem.2012, 893-896.
  5. Teng, Y.; Lu, J.; Toy, P. H. Rasta Resin-PPh3-NBniPr2 and its Use in One-Pot Wittig Reaction Cascades. Chem. Asian J.2012, 7, 351-359.
  6. Lu, J.; Toy, P. H. Reactions of Nitroalkenes with Sulfur Ylides or Nitroalkanes Catalyzed by Amine-Thiourea Bifunctional Polymeric Organocatalysts. Synlett2011, 3085-3090.
  7. Hermeke, J.; Toy, P. H. Phosphonium Ion Tagged Chiral Phosphoric Acids and Their Application in Friedel-Crafts Reactions of Indoles. Tetrahedron 2011, 67, 4103-4109.
  8. Lu, J.; Toy, P. H. Tandem One-Pot Wittig/Reductive Aldol Condensation Reactions in which the Waste from One Process Catalyzes a Subsequent Reaction. Chem. Asian J.2011, 6, 2251-2254.
  9. Lu, J.; Toy, P. H. Organocatalytic Decarboxylative Doebner-Knoevenagel Reactions Between Arylaldehydes and Mono-Ethyl Malonate Mediated by a Bifunctional Polymeric Catalyst. Synlett2011, 1723-1726.
  10. Fu, M. Y.; Guo, J.; Toy, P. H. Synthesis of Dienol Ethers Using the Phosphine-Catalyzed Alkyne Isomerization Reaction. Synlett 2011, 989-991.
  11. Lu, J.; Toy, P. H. Rasta Resin-DMAP and its Use as a Recyclable Catalyst for the Addition of Carbon Dioxide to Epoxides. Synlett 2011, 659-662.
  12. Teng, Y.; Toy, P. H. Rasta Resin-PPh3BnCl and its Use in Chromatography-Free Carbonyl Cyanosilylation Reactions. Synlett 2011, 551-554.
  13. Leung, P. S.-W.; Teng, Y.; Toy, P. H. Chromatography-Free Wittig Reactions Using a Bifunctional Polymeric Reagent. Org. Lett. 2010, 12, 4996-4999.
  14. Kwong, C. K.-W.; Fu, M. Y.; Law, H. C.-H.; Toy, P. H. Isomerization of Electron-Poor Alkynes to the Corresponding (E,E)-1,3-Dienes Using a Bifunctional Polymeric Catalyst Bearing Triphenylphosphine and Phenol Groups. Synlett 2010, 2617-2620.
  15. Leung, P. S.-W.; Teng, Y.; Toy, P. H. Rasta Resin-PPh3 and its Use in Chromatography-Free Wittig Reactions. Synlett 2010, 1997-2001.
  16. But, T. Y. S.; Lu, J.; Toy, P. H. Organocatalytic Mitsunobu Reactions Using 3,5-Dinitrobenzoic Acid. Synlett 2010, 1115-1117.
  17. Cividino, P.; Dheu-Andries, M.-L.; Ou, J.; Milet, A. ; Py, S.; Toy, P. H. Mechanistic Investigations of the Tributylphospine-Mediated Nitrone Reduction Reaction and Its Application in Cyclic Imine Synthesis. Tetrahedron Lett. 2009, 50, 7038-7042.
  18. Lu, J.; Toy, P. H. Organic Polymer Supports for Synthesis and for Reagent and Catalyst Immobilization. Chem. Rev.2009, 109, 815-838. [PDF]
  19. Lam, Y.-L.; Yang, D.; Chan, C.-Y.; Chan, K.-Y.; Toy, P. H. Use of Water-Compatible Polystyrene-Polyglycidol Resin for the Separation and Recovery of Dissolved Precious Metal Salts. Ind. Chem. Eng. Res.2009, 48, 4975-4979. [PDF]
  20. Kwong, C. K.-W.; Fu, M. Y.; Lam, C. S.-L.; Toy, P. H. The Phosphine-Catalyzed Alkyne to 1,3-Diene Isomerization Reaction. Synthesis2008, 2307-2317. [PDF]
  21. He, R.; Toy, P. H.; Lam, Y. Polymer-Supported Hantzsch 1,4-Dihydropyridine Ester: An Efficient Biomimetic Hydrogen Source. Adv. Synth. Catal.2008, 350, 54-60. [PDF]
  22. But, T. Y. S.; Toy, P. H. The Mitsunobu Reaction: Origin, Mechanism, Improvements and Applications. Chem. Asian J.2007, 2, 1340-1355. [PDF]
  23. Yamamoto, Y.; Kawano, Y.; Toy, P. H.; Togo, H. PhI- and Polymer-Supported PhI-Catalyzed Oxidative Conversion of Ketones and Alcohols to a-Tosyloxyketones with m-Chloroperbenzoic Acid and p-Toluenesulfonic Acid. Tetrahedron2007, 63, 4680-4687. [PDF]
  24. Shang, Y.; But, T. Y. S.; Togo, H.; Toy, P. H. Macroporous Polystyrene-Supported (Diacetoxyiodo)benzene: An Efficient Heterogeneous Oxidizing Reagent. Synlett2007, 67-70. [PDF]
  25. Kwong, C. K.-W.; Huang, R.; Zhang, M.; Shi, M.; Toy, P. H. Bifunctional Polymeric Organocatalysts and Their Application in the Cooperative Catalysis of Morita-Baylis-Hillman Reactions. Chem. Eur. J.2007, 13, 2369-2376. [PDF]
  26. Chung, C. W. Y.; Toy, P. H. Multipolymer Reaction System for Selective Aerobic Alcohol Oxidation: Use of Multiple Different Polymer-Supported Ligands. J. Comb. Chem.2007, 9, 115-120. [PDF] [Supporting Info]
  27. Toy, P. H. Nanoscale Catalysis of Organic Molecule Transformations. J. Exp. Nanosci.2006, 1, 397. [PDF]