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Teaching Staff

Professor SUN, Hongzhe

Professor SUN, Hongzhe

Department of Chemistry, Faculty of Science, HKU

B.Sc.(Huabei), M.Sc. CAS(wuhan), Ph.D. 1996(London)


  • 2859 8974
  • 304 Chong Yuet Ming Chemistry Building, University of Hong Kong, Pokfulam Road, Hong Kong

Research Area:

  • Biological Inorganic Chemistry
  • Medicinal Chemistry and Inorganic Structural Biology
  • Metallomics and Metalloproteomics

 

Achievements:

  • Member of Editorial Board, Metallomics (RSC), Journal of Inorganic Biochemistry (Elsevier)
  • Series Editor of Metallobiology (RSC)
  • Croucher Senior Research Fellow (2010-2011)
  • HKU Outstanding Researcher Award (2009-2010)
  • Outstanding Young Scholar Award, NSFC (2005)
  • HKU Outstanding Young Researcher Award (2004-2005)

 

Publications:

  1. Xia W, Li HY, Yang XM, Wong KB, Sun H, "Metallo-GTPase HypB from Helicobacter pylori and its interaction with nickel chaperone protein HypA" J. Biol. Chem. 2012, 287, 6753-6763.
  2. Li HY, Sun H, "Recent advances in bioinorganic chemistry of bismuth" Curr. Opin. Chem. Biol. 2012, 16, 74-83.
  3. Tsang CN, Ho KS, Sun H, Chan WT, "Tracking bismuth drug uptake in single Helicobacter pylori cells" J. Am. Chem. Soc. 2011, 133, 7355-7357.
  4. Wang XH, Du XB, Li HY, Chan DSB, Sun H, "The effect of the extracellular domain of human copper transporter (hCTR1) on cisplatin activation" Angew. Chem. Int. Ed. 2011, 50, 2706-2711. (Frontispiece)
  5. Sun H (ed.), "Biological chemistry of arsenic, antimony and bismuth", John Wiley & Sons, 2011.
  6. Cun SJ, Sun H, "A zinc-binding site by negative selection induces metallodrug susceptibility in an essential chaperonin" Proc. Natl Acad. Sci. USA 2010, 107, 4943- 4948.
  7. Xia W, Li HY, Sze KH, Sun H, "Structure of a nickel chaperone, HypA from Helicobacter pylori reveals two distinct metal binding sites" J. Am. Chem. Soc. 2009, 131, 10031- 10040.
  8. Sun XS, Tsang CN, Sun H, "Identification of binding proteins of metallodrugs by (metallo)proteomics" Metallomics 2009, 1, 25-31.
  9. Cun SJ, Li HY, Ge RG, Lin MCM, Sun H, "A histidine- and cysteine-rich metal binding domain at the C-terminus of heat- shock protein A from Helicobacter pylori: implication for nickel homeostasis and bismuth susceptibility" J. Biol. Chem. 2008, 283, 15142-15151.
  10. Ge RG, Sun H, "Bioinorganic chemistry of bismuth and antimony: target sites for metallodrugs" Acc. Chem. Res., 2007, 40, 267-274.
  11. Yang N, Tanner JA, Zheng BJ, Watt RM, He ML, Lu LY, Jiang J-Q, Shum K-T, Lin Y-P, Wong KL, Lin MCM, Kung HF, Sun H, Huang JD, "Bismuth complexes inhibit the SARS coronavirus" Angew. Chem. Int. Ed. 2007, 46, 6464-6468.