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Teaching Staff

Professor WONG, Anderson On Lam

Professor WONG, Anderson On Lam

Professor, School of Biological Sciences, Faculty of Science, HKU

BSc(HK); MPhil(HK); PhD(Alberta)

  • 3917 3863
  • 2858 3477
  • KBSB 4S12

Teaching Areas

  • Reproduction & Reproductive Biotechnology
  • Animal Physiology & Environmental Adaptation
  • Human Physiology

Research Interests

  • Regulation & signal transduction for pituitary hormones in fish models
  • Autocrine/paracrine functions of pituitary hormones in fish pituitary
  • Novel mechanisms for gene transcription in somatotropic & gonatotropic axis
  • Novel regulators & underlying mechanisms for feeding control in fish models
  • Functional crosstalk between feeding regulators & pituitary hormones in fish

Current Research

  • NKB & NKBRP as novel regulators for somatolactin & prolactin in carp pituitary
  • Intracellular feedback repressors for growth hormone-induced IGF-I expression
  • Novel mechanisms for IGF-I promoter activation induced by growth hormone
  • Autocrine/paracrine functions of pituitary hormones in carp pituitary cells
  • Spexin as a novel satiety factor in goldfish via central & peripheral actions
  • Pituitary actions of spexin & its functional crosstalk with growth hormone
  • Leptin & adiponectin on pituitary hormone secretion/expression in carp model

Research Team

Lab technician:            Ms Wendy Kit Wan Ko

Research associate:   Dr Mulan He

Research assistant:    Ms Martina Mang Leng Lei

PhD students:              Ms Jin Bai, Mr Zheng Yunhua

MPhil student:             Mr Dongliang Li

Project students:         Mr Ching Sum Ho, Ms Lok Yee Wan

Fellowships

  • Restacom Postdoctoral Fellowship (1994-95), University of Toronto, Canada

Publications and News

  • C.Y. Lin, J. Bai, M. He, and A.O.L. Wong (2018)  Grass carp prolactin gene: Structural organization and signal transduction for PACAP-induced prolactin promoter activity.  Sci Rep 8:4655 / DOI:10.1038/s41598-018-23092-0.
  • G. Hu, M. He, W.K.W. Ko, and A.O.L. Wong (2017)  TAC1 gene products regulate pituitary hormone secretion and gene expression in prepubertal grass carp pituitary cells.  Endocrinology 158:1-22.
  • A. Ma, M. He, J. Bai, M.K.H. Wong, W.K.W. Ko, and A.O.L. Wong (2017)  Dual role of insulin in spexin regulation :  Functional link between food intake and spexin expression in fish model.  Endocrinology 158:560-577.
  • G. Hu, M. He and A.O.L. Wong (2016)  Novel functional role of NK3R expression in the potentiating effects on somatolactin a autoregulation in grass carp pituitary cells.  Sci Rep 6:36102-36114 / doi: 10.1038
  • X. Jiang, J. Xiao, M. He, A. Ma, and A.O.L. Wong (2016)  Type II SOCS as feedback repressor for GH-induced IGF1 expression in carp hepatocytes.  J Endocrinol 229:171-186
  • C. Lin, X. Jiang, G. Fu, W.K.W. Ko, and A.O.L. Wong (2015)  Grass carp prolactin:  Molecular cloning, tissue expression, intrapituitary autoregulation by prolactin and paracrine regulation by growth hormone and luteinizing hormone.  Mol Cell Endocrinol 399:367-283
  • Q. Jiang, M. He, W.K.O. Ko and A.O.L. Wong (2014) Kisspeptin induction of somatolactin α release in goldfish pituitary cells:  Functional role of cAMP/PKA-, PLC/PKC-, and Ca2+/calmodulin-dependent cascades. Am J Physiol Endocrinol Metab 307:E872-884.
  • G. Hu, M. He, W.K.W. Ko, C. Lin, and A.O.L. Wong (2014)   Novel pituitary actions of TAC3 gene products in fish model: -  Receptor specificity and signal transduction for prolactin and somatolactin α regulation by neurokinin B (NKB) and NKB- related peptide in carp pituitary cells.  Endocrinology 155:3582-3596.
  • M.K.H. Wong, K.H. Sze, T. Chen, C.K. Cho, Henry C.H. Law, I.K. Chu, and A.O.L. Wong (2013)  Goldfish Spexin: Solution structure and novel function as a satiety factor in feeding control.  Am. J. Physiol. Endocrinol. Metab 305:E348-E366
  • Q. Jiang and A.O.L. Wong (2013)  Signal transduction mechanisms for autocrine/paracrine regulation of somatolactin α secretion and synthesis in carp pituitary cells by somatolactin α and β.  Am. J. Physiol. Endocrinol. Metab 304:E176-E186.

Awards and Honours

  • HKU Long Services Award (2014), Communication & External Affairs Office, HKU
  • GRF Merit Award (2012, HK$20,000), University Research Committee, HKU
  • GRF Incentive Award (2011, HK$20,000), University Research Committee, HKU
  • Faculty Incentive Award (2011, HK$40,000), Faculty of Science, HKU
  • GRF Merit Award (2010, HK$50,000), University Research Committee, HKU
  • Award for Teaching Excellence (2009, HK$20,000), Faculty of Science, HKU
  • GRF Merit Award (2008-2009, HK$50,000/year), University Research Committee, HKU
  • CERG Merit Award (2003-2007, HK$50,000/year), University Research Committee, HKU
  • Honourable Mention Award (2002), Education Awards Program, Academic Council, HKU
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