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Teaching Staff

Professor CHOW, Billy Kwok Chong

Professor CHOW, Billy Kwok Chong

Professor, Chair of Endocrinology, School of Biological Sciences, School of Biological Sciences, Faculty of Science, HKU

B.Sc. Hon. (First Class), Physiology, University of British Columbia. Ph.D. Biochemistry, University of British Columbia

  • 2299 0850
  • 2559 9114
  • KBSB 4N12

Teaching Areas

  • Endocrinology
  • Molecular Biology

Research Interests

  • Bioactive Peptides and G Protein-coupled Receptors
  • Neuroendocrinology of Secretin

Current Research

  • Role of Secretin and its receptor in thirst regulatory neural circuits
  • Co-evolution of function and structure of PACAP with the hypothalamo-pituitary axis from invertebrates to vertebrates.
  • Molecular Mechanisms Underlying the Progressive Development of Pulmonary Arterial Hypertension in Secretin Knockout Mice.

Research Team


Ms. Elisa Lau


Dr. On Sai Wun

Dr. Singh Kailash


PhD students:

Ms. Mak Oi Kwan

Mr. Duraisamy Karthi

Mr. Zhang Fengwei

Mr. Liu Yuchu

Mr. Luo Yifan

Mr. Shaik Abdullah Nawabjan


Research Assistant:

Ms. Ng Ka Man



  • Croucher Senior Research Fellow
  • University of Kyoto
  • University of British Columbia

Publications and News

  • JJ Bai, BKC Chow 2017 Secretin is involved in sodium conservation through the renin-angiotensin-aldosterone system. FASEB Journal 31(4): 1689-1697.
  • JSW On, C Duan, BKC Chow, LTO Lee 2015 Functional pairing of class B1 ligand- GPCR in cephalochordate provides evidence of the origin of PTH and PACAP/glucagon receptor family. Mol. Biol. Evol. 32(8):2048-59.
  • LTO Lee, SYL Ng, JYS Chu, R Sekar, KG Harikumar, LJ Miller, BKC Chow 2014 Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex. FASEB J 28(6):2632-44.
  • R Sekar, BKC Chow 2014 SCTR-knockout mice are resistant to high-fat diet-induced obesity and exhibit impaired intestinal lipid absorption. FASEB J 13(2):4753-56.
  • Zhang L, Chung, SK, BKC Chow 2014 The Knockout of Secretin in Cerebellar Purkinje Cells Impairs Mouse Motor Coordination and Motor Learning. Neuropsychopharmacology 39(6):1460-68.
  • CYY Cheng, JYS Chu, BKC Chow 2011 Central and peripheral administration of secretin inhibits food intake in mice through the activation of the melanocortin system. Neuropsychopharmacology. 36(2):459-71.
  • VHY Lee, LTO Lee, JYS Chu, IPY Lam, FKY Siu, H Vaudry, BKC Chow 2010 An indispensable role of secretin in mediating the osmoregulatory functions of angiotensin II. FASEB Journal. 24(12):5024-5032.
  • JYS Chu, LTO Lee, CH Lai, H Vaudry, YS Chan, WH Yung, BKC Chow 2009 SCT as a neurohypophysial factor regulating body fluid homeostasis. Proc Natl Acad Sci USA 106(37):15961-66.
  • LTO Lee, FKY Siu, JKV Tam, ITY Lau, AOL Wong, MCM Lin, H Vaudry, BKC Chow 2007 Discovery of GHRHs and receptors in non-mammalian vertebrates Proc Natl Acad Sci USA 104(7):2133-38.
  • WH Yung, PS Leung, SSM Ng, J Zhang, SCY Chan, BKC Chow 2001 SCT facilitates GABA transmissionin the cerebellum. J Neurosci 21(18):7063-68

Awards and Honours

  • 2017        Alumni Builder Award, University of British Columbia
  • 2010        Research Output Prize, The University of Hong Kong.
  • 2007        Akira Arimura Young Investigator Award: By the international  VIP/PACAP society.  In memory of Prof Arimura who founded this research area, I was awarded the first Akira Arimura young investigator award in 2007 in recognition of my contributions in understanding the pleiotropic activities of secretin in our body.
  • 2005        Grace Pickford Medal: By the International Federation of Comparative Endocrine Societies (IFCE). This is the most prestigious award for comparative endocrinologists, given out once every 4 years in the international comparative endocrinology meeting. I am the first scientist from Hong Kong receiving this honor.
  • Outstanding Researcher Award, By The University of Hong Kong.
  • 2004        Croucher Senior Research Fellow by Croucher Foundation.
  • 1995         Travel award for young scientist, International congress Neuroscience.
  • 1992          Medical Research Council, Canada, Postdoctoral Fellowship. Highly competitive as there were only 30 of these postdoctoral fellows given out in 1992 in Canada.
  • 1986-91     Medical Research Council, Canada, Studentship.
  • 1989          Special travel fund for young scientists (International Society on Thrombosis and Haemostasis).
  • 1986          NSERC Summer Studentship, Canada.
  • 1983-85     University of BC Scholarship, UBC.
  • 1983-84     Quan Memorial Scholarship, UBC.