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AI-Powered Tool RevolutioniSes Electron Microscopy for Cellular Imaging

cellular imaging

Image modified from the journal paper

Professor Haibo JiangResearchers // Professor Haibo JIANG, Associate Professor of the Department of Chemistry, and his PhD students Chixiang LU and Gu CHEN, and researchers Dr Kai CHEN and Dr Heng QIU
HKU Partnership // Department of Electrical and Electronic Engineering
Collaborator // The University of Western Australia

 

Researchers have developed an advanced AI tool called 'EMDiffuse' that significantly enhances the imaging capabilities of electron microscopes. This innovation allows scientists to transform low-quality images into sharp, high-resolution visuals, making it possible to study intricate cell structures in unprecedented detail. EMDiffuse also improves 3D imaging, helping researchers better understand the complex architecture and interactions of structures within cells, such as mitochondria and the endoplasmic reticulum. This breakthrough opens up exciting possibilities for exploring the nanoscale world of cells and uncovering new insights into their functions.
 
 
研究人員開發全新AI 工具「EMDiffuse」,大幅提升電子顯微鏡的成像品質與解析度,讓科學家能以前所未有的細緻程度觀察細胞內部結構,推動細胞納米尺度研究邁向新里程碑。

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Journal paper: Diffusion-based deep learning method for augmenting ultrastructural imaging and volume electron microscopy (published in Nature Communications, 2024)


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